Alaska Airlines flight AS 4216: Multiple routes

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FLIGHT SCHEDULE
Direct Codeshare Flights:
Tue 00:48 Phoenix Sky Harbor (PHX) 4 07:01 Ronald Reagan Washington (DCA) 2
AS 4216 Non-stop Airbus A321neo (32Q) 4:13 Operates only on 2026-01-06
Codeshare flight, operated by American Airlines.(AA 1608)
Daily 00:53 Phoenix Sky Harbor (PHX) 4 07:05 Ronald Reagan Washington (DCA) 2
AS 4216 Non-stop Airbus A321neo (32Q) 4:12 Effective 2025-12-18 through 2026-01-05
Codeshare flight, operated by American Airlines.(AA 1608)
Sat,Sun 08:44 Orlando (MCO) B 10:47 Chicago O'Hare (ORD) 3
AS 4216 Non-stop Airbus A321 (321) 3:03 Effective 2025-10-04 through 2025-10-05
Codeshare flight, operated by American Airlines.(AA 1842)
Daily 10:17 Greensboro/High Point (GSO) 11:35 Ronald Reagan Washington (DCA) 2
AS 4216 Non-stop Canadair CRJ 700 (CR7) 1:18 Effective from 2026-02-12
Codeshare flight, operated by American Airlines.(AA 5518)
Daily 10:20 Greensboro/High Point (GSO) 11:38 Ronald Reagan Washington (DCA) 2
AS 4216 Non-stop Canadair CRJ 700 (CR7) 1:18 Effective 2025-12-03 through 2025-12-17
Codeshare flight, operated by American Airlines.(AA 5518)
Mon-Fri,Sun 10:50 Los Angeles (LAX) 16:10 George Bush, Houston (IAH) A
AS 4216 Non-stop Embraer EMB 175 (E75) 3:20 Effective 2025-11-16 through 2025-11-21
Codeshare flight, operated by American Airlines.(AA 6389)
Mon,Tue,Sun 10:50 Los Angeles (LAX) 16:10 George Bush, Houston (IAH) A
AS 4216 Non-stop Embraer EMB 175 (E75) 3:20 Effective 2025-11-30 through 2025-12-02
Codeshare flight, operated by American Airlines.(AA 6389)
Daily 14:50 Chicago O'Hare (ORD) 3 16:53 Fort Wayne (FWA)
AS 4216 Non-stop Canadair CRJ 700 (CR7) 1:03 Effective 2025-10-26 through 2025-11-01
Codeshare flight, operated by American Airlines.(AA 4917)
Mon-Fri,Sun 14:50 Chicago O'Hare (ORD) 3 16:50 Fargo (FAR)
AS 4216 Non-stop Embraer EMB 170 / EMB 175 (E70) 2:00 Effective 2025-11-23 through 2025-11-28
Codeshare flight, operated by American Airlines.(AA 3620)
Daily 16:30 Cleveland Hopkins (CLE) 17:08 Chicago O'Hare (ORD) 3
AS 4216 Non-stop Canadair CRJ 700 (CR7) 1:38 Effective 2025-08-09 through 2025-10-03
Codeshare flight, operated by American Airlines.(AA 6527)
Mon-Fri,Sun 16:40 George Bush, Houston (IAH) A 18:46 Los Angeles (LAX)
AS 4216 Non-stop Embraer EMB 175 (E75) 4:06 Effective 2025-11-16 through 2025-11-21
Codeshare flight, operated by American Airlines.(AA 6389)
Mon,Tue,Sun 16:40 George Bush, Houston (IAH) A 18:46 Los Angeles (LAX)
AS 4216 Non-stop Embraer EMB 175 (E75) 4:06 Effective 2025-11-30 through 2025-12-02
Codeshare flight, operated by American Airlines.(AA 6389)
Daily 16:44 Chicago O'Hare (ORD) 3 20:00 New York John F. Kennedy (JFK) 8
AS 4216 Non-stop Boeing 737-800 (738) 2:16 Effective 2025-05-05 through 2025-06-04
Codeshare flight, operated by American Airlines.(AA 696)
Daily 17:10 Chicago O'Hare (ORD) 3 20:30 New York John F. Kennedy (JFK) 8
AS 4216 Non-stop Boeing 737-800 (738) 2:20 Valid until 2025-05-04
Codeshare flight, operated by American Airlines.(AA 696)
Mon-Fri,Sun 17:45 Fargo (FAR) 19:50 Chicago O'Hare (ORD) 3
AS 4216 Non-stop Embraer EMB 170 / EMB 175 (E70) 2:05 Effective 2025-11-23 through 2025-11-28
Codeshare flight, operated by American Airlines.(AA 3620)
Daily 18:29 Chicago O'Hare (ORD) 3 21:59 New York John F. Kennedy (JFK) 8
AS 4216 Non-stop Boeing 737-800 (738) 2:30 Effective 2025-10-06 through 2025-10-25
Codeshare flight, operated by American Airlines.(AA 696)
Wed-Fri 18:49 New York LaGuardia (LGA) B 20:40 Chicago O'Hare (ORD) 3
AS 4216 Non-stop Boeing 737-800 (738) 2:51 Effective 2025-08-06 through 2025-08-08
Codeshare flight, operated by American Airlines.(AA 3073)
Tue 20:05 Dallas Fort Worth (DFW) 20:53 Tyler (TYR)
AS 4216 Non-stop Embraer EMB 170 / EMB 175 (E70) 0:48 Operates only on 2025-07-01
Codeshare flight, operated by American Airlines.(AA 4166)
Daily 20:20 Chicago O'Hare (ORD) 3 21:21 Milwaukee (MKE)
AS 4216 Non-stop Canadair CRJ 700 (CR7) 1:01 Effective 2025-11-02 through 2025-11-15
Codeshare flight, operated by American Airlines.(AA 6366)
Sat 20:20 Chicago O'Hare (ORD) 3 21:21 Milwaukee (MKE)
AS 4216 Non-stop Canadair CRJ 700 (CR7) 1:01 Effective 2025-11-22 through 2025-11-29
Codeshare flight, operated by American Airlines.(AA 6366)
Daily 20:20 Chicago O'Hare (ORD) 3 22:22 Fort Wayne (FWA)
AS 4216 Non-stop Canadair CRJ 700 (CR7) 1:02 Effective 2026-01-07 through 2026-02-11
Codeshare flight, operated by American Airlines.(AA 4917)
Daily 22:59 Dallas Fort Worth (DFW) 23:46 Tyler (TYR)
AS 4216 Non-stop Embraer EMB 175 (E75) 0:47 Effective 2025-06-05 through 2025-06-30
Codeshare flight, operated by American Airlines.(AA 4166)
Wed,Thu 22:59 Dallas Fort Worth (DFW) 23:46 Tyler (TYR)
AS 4216 Non-stop Embraer EMB 175 (E75) 0:47 Effective 2025-07-02 through 2025-07-03
Codeshare flight, operated by American Airlines.(AA 4166)
Daily 22:59 Dallas Fort Worth (DFW) 23:49 Tyler (TYR)
AS 4216 Non-stop Embraer EMB 175 (E75) 0:50 Effective 2025-07-05 through 2025-08-05
Codeshare flight, operated by American Airlines.(AA 4166)
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This flight number is listed as serving the following routes:


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Alaska Airlines flight AS 4216: Multiple routes
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Select flight date:
FLIGHT SCHEDULE
Direct Codeshare Flights:
Alaska Airlines AS4216
00:48
Phoenix Sky Harbor (PHX) 4

07:01
Ronald Reagan Washington (DCA) 2
Operates only on 2026-01-06
Mon
-
Tue
Wed
-
Thu
-
Fri
-
Sat
-
Sun
-
Codeshare flight, operated by American Airlines. (AA 1608)
Duration: 4:13, non-stop
Airbus A321neo (32Q)
Alaska Airlines AS4216
00:53
Phoenix Sky Harbor (PHX) 4

07:05
Ronald Reagan Washington (DCA) 2
Effective 2025-12-18 through 2026-01-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 1608)
Duration: 4:12, non-stop
Airbus A321neo (32Q)
Alaska Airlines AS4216
08:44
Orlando (MCO) B

10:47
Chicago O'Hare (ORD) 3
Effective 2025-10-04 through 2025-10-05
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 1842)
Duration: 3:03, non-stop
Airbus A321 (321)
Alaska Airlines AS4216
10:17
Greensboro/High Point (GSO)

11:35
Ronald Reagan Washington (DCA) 2
Effective from 2026-02-12
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 5518)
Duration: 1:18, non-stop
Canadair CRJ 700 (CR7)
Alaska Airlines AS4216
10:20
Greensboro/High Point (GSO)

11:38
Ronald Reagan Washington (DCA) 2
Effective 2025-12-03 through 2025-12-17
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 5518)
Duration: 1:18, non-stop
Canadair CRJ 700 (CR7)
Alaska Airlines AS4216
10:50
Los Angeles (LAX)

16:10
George Bush, Houston (IAH) A
Effective 2025-11-16 through 2025-11-21
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Codeshare flight, operated by American Airlines. (AA 6389)
Duration: 3:20, non-stop
Embraer EMB 175 (E75)
Alaska Airlines AS4216
10:50
Los Angeles (LAX)

16:10
George Bush, Houston (IAH) A
Effective 2025-11-30 through 2025-12-02
Mon
Tue
Wed
-
Thu
-
Fri
-
Sat
-
Sun
Codeshare flight, operated by American Airlines. (AA 6389)
Duration: 3:20, non-stop
Embraer EMB 175 (E75)
Alaska Airlines AS4216
14:50
Chicago O'Hare (ORD) 3

16:53
Fort Wayne (FWA)
Effective 2025-10-26 through 2025-11-01
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 4917)
Duration: 1:03, non-stop
Canadair CRJ 700 (CR7)
Alaska Airlines AS4216
14:50
Chicago O'Hare (ORD) 3

16:50
Fargo (FAR)
Effective 2025-11-23 through 2025-11-28
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Codeshare flight, operated by American Airlines. (AA 3620)
Duration: 2:00, non-stop
Embraer EMB 170 / EMB 175 (E70)
Alaska Airlines AS4216
16:30
Cleveland Hopkins (CLE)

17:08
Chicago O'Hare (ORD) 3
Effective 2025-08-09 through 2025-10-03
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 6527)
Duration: 1:38, non-stop
Canadair CRJ 700 (CR7)
Alaska Airlines AS4216
16:40
George Bush, Houston (IAH) A

18:46
Los Angeles (LAX)
Effective 2025-11-16 through 2025-11-21
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Codeshare flight, operated by American Airlines. (AA 6389)
Duration: 4:06, non-stop
Embraer EMB 175 (E75)
Alaska Airlines AS4216
16:40
George Bush, Houston (IAH) A

18:46
Los Angeles (LAX)
Effective 2025-11-30 through 2025-12-02
Mon
Tue
Wed
-
Thu
-
Fri
-
Sat
-
Sun
Codeshare flight, operated by American Airlines. (AA 6389)
Duration: 4:06, non-stop
Embraer EMB 175 (E75)
Alaska Airlines AS4216
16:44
Chicago O'Hare (ORD) 3

20:00
New York John F. Kennedy (JFK) 8
Effective 2025-05-05 through 2025-06-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 696)
Duration: 2:16, non-stop
Boeing 737-800 (738)
Alaska Airlines AS4216
17:10
Chicago O'Hare (ORD) 3

20:30
New York John F. Kennedy (JFK) 8
Valid until 2025-05-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 696)
Duration: 2:20, non-stop
Boeing 737-800 (738)
Alaska Airlines AS4216
17:45
Fargo (FAR)

19:50
Chicago O'Hare (ORD) 3
Effective 2025-11-23 through 2025-11-28
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Codeshare flight, operated by American Airlines. (AA 3620)
Duration: 2:05, non-stop
Embraer EMB 170 / EMB 175 (E70)
Alaska Airlines AS4216
18:29
Chicago O'Hare (ORD) 3

21:59
New York John F. Kennedy (JFK) 8
Effective 2025-10-06 through 2025-10-25
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 696)
Duration: 2:30, non-stop
Boeing 737-800 (738)
Alaska Airlines AS4216
18:49
New York LaGuardia (LGA) B

20:40
Chicago O'Hare (ORD) 3
Effective 2025-08-06 through 2025-08-08
Mon
-
Tue
-
Wed
Thu
Fri
Sat
-
Sun
-
Codeshare flight, operated by American Airlines. (AA 3073)
Duration: 2:51, non-stop
Boeing 737-800 (738)
Alaska Airlines AS4216
20:05
Dallas Fort Worth (DFW)

20:53
Tyler (TYR)
Operates only on 2025-07-01
Mon
-
Tue
Wed
-
Thu
-
Fri
-
Sat
-
Sun
-
Codeshare flight, operated by American Airlines. (AA 4166)
Duration: 0:48, non-stop
Embraer EMB 170 / EMB 175 (E70)
Alaska Airlines AS4216
20:20
Chicago O'Hare (ORD) 3

21:21
Milwaukee (MKE)
Effective 2025-11-02 through 2025-11-15
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 6366)
Duration: 1:01, non-stop
Canadair CRJ 700 (CR7)
Alaska Airlines AS4216
20:20
Chicago O'Hare (ORD) 3

21:21
Milwaukee (MKE)
Effective 2025-11-22 through 2025-11-29
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Codeshare flight, operated by American Airlines. (AA 6366)
Duration: 1:01, non-stop
Canadair CRJ 700 (CR7)
Alaska Airlines AS4216
20:20
Chicago O'Hare (ORD) 3

22:22
Fort Wayne (FWA)
Effective 2026-01-07 through 2026-02-11
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 4917)
Duration: 1:02, non-stop
Canadair CRJ 700 (CR7)
Alaska Airlines AS4216
22:59
Dallas Fort Worth (DFW)

23:46
Tyler (TYR)
Effective 2025-06-05 through 2025-06-30
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 4166)
Duration: 0:47, non-stop
Embraer EMB 175 (E75)
Alaska Airlines AS4216
22:59
Dallas Fort Worth (DFW)

23:46
Tyler (TYR)
Effective 2025-07-02 through 2025-07-03
Mon
-
Tue
-
Wed
Thu
Fri
-
Sat
-
Sun
-
Codeshare flight, operated by American Airlines. (AA 4166)
Duration: 0:47, non-stop
Embraer EMB 175 (E75)
Alaska Airlines AS4216
22:59
Dallas Fort Worth (DFW)

23:49
Tyler (TYR)
Effective 2025-07-05 through 2025-08-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 4166)
Duration: 0:50, non-stop
Embraer EMB 175 (E75)
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This flight number is listed as serving the following routes:
  • Chicago O'Hare (ORD) - Fort Wayne (FWA)
  • Chicago O'Hare (ORD) - Milwaukee (MKE)
  • Chicago O'Hare (ORD) - New York John F. Kennedy (JFK)
  • Cleveland Hopkins (CLE) - Chicago O'Hare (ORD)
  • Dallas Fort Worth (DFW) - Tyler (TYR)
  • Fargo (FAR) - Chicago O'Hare (ORD)
  • Greensboro/High Point (GSO) - Ronald Reagan Washington (DCA)
  • Los Angeles (LAX) - George Bush, Houston (IAH)
  • New York LaGuardia (LGA) - Chicago O'Hare (ORD)
  • Orlando (MCO) - Chicago O'Hare (ORD)
  • Phoenix Sky Harbor (PHX) - Ronald Reagan Washington (DCA)
All Alaska Airlines flights
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