American Airlines flight AA 2121: Multiple routes

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FLIGHT SCHEDULE
Direct Flights:
Mon-Fri,Sun 05:00 Kansas City (MCI) 06:39 Chicago O'Hare (ORD) 3
AA 2121 Non-stop Boeing 737-800 (738) 1:39 Effective 2025-06-06 through 2025-06-13
Daily 05:00 Kansas City (MCI) 06:39 Chicago O'Hare (ORD) 3
AA 2121 Non-stop Boeing 737-800 (738) 1:39 Effective 2025-06-14 through 2025-07-04
Daily 05:44 Kansas City (MCI) 07:25 Chicago O'Hare (ORD) 3
AA 2121 Non-stop Boeing 737-800 (738) 1:41 Effective 2025-07-05 through 2025-08-05
Daily 06:00 Tampa (TPA) 07:10 Miami (MIA)
AA 2121 Non-stop Boeing 737 MAX 8 (7M8) 1:10 Effective 2025-10-26 through 2025-11-01
Daily 12:25 Chicago O'Hare (ORD) 3 15:44 Boston Logan (BOS) B
AA 2121 Non-stop Boeing 737-800 (738) 2:19 Effective 2026-01-07 through 2026-02-11
Mon-Fri,Sun 15:00 Ronald Reagan Washington (DCA) 2 16:17 Pittsburgh (PIT)
AA 2121 Non-stop Airbus A319 (319) 1:17 Valid until 2025-05-04
Daily 15:15 Phoenix Sky Harbor (PHX) 4 22:01 Detroit (DTW) E
AA 2121 Non-stop Boeing 737-800 (738) 3:46 Effective 2025-08-06 through 2025-09-02
Daily 15:15 Phoenix Sky Harbor (PHX) 4 22:04 Detroit (DTW) E
AA 2121 Non-stop Boeing 737-800 (738) 3:49 Effective 2025-09-03 through 2025-10-05
Daily 16:09 Phoenix Sky Harbor (PHX) 4 22:59 Detroit (DTW) E
AA 2121 Non-stop Boeing 737-800 (738) 3:50 Effective 2025-05-05 through 2025-05-24
Daily 16:09 Phoenix Sky Harbor (PHX) 4 22:59 Detroit (DTW) E
AA 2121 Non-stop Boeing 737-800 (738) 3:50 Effective 2025-05-26 through 2025-06-04
Daily 16:35 Phoenix Sky Harbor (PHX) 4 23:22 Detroit (DTW) E
AA 2121 Non-stop Boeing 737-800 (738) 3:47 Effective 2025-10-06 through 2025-10-25
Mon-Fri,Sun 17:02 Pittsburgh (PIT) 18:14 Ronald Reagan Washington (DCA) 2
AA 2121 Non-stop Airbus A319 (319) 1:12 Valid until 2025-05-04
Daily 21:20 Phoenix Sky Harbor (PHX) 4 22:04 Fresno (FAT)
AA 2121 Non-stop Airbus A320 (320) 1:44 Effective 2025-11-02 through 2025-12-17
Daily 21:20 Phoenix Sky Harbor (PHX) 4 22:09 Fresno (FAT)
AA 2121 Non-stop Airbus A320 (320) 1:49 Effective 2025-12-18 through 2026-01-05
Daily 21:20 Phoenix Sky Harbor (PHX) 4 22:03 Fresno (FAT)
AA 2121 Non-stop Airbus A320 (320) 1:43 Effective from 2026-02-12
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This flight number is listed as serving the following routes:


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American Airlines flight AA 2121: Multiple routes
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Select flight date:
FLIGHT SCHEDULE
Direct Flights:
American Airlines AA2121
05:00
Kansas City (MCI)

06:39
Chicago O'Hare (ORD) 3
Effective 2025-06-06 through 2025-06-13
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Duration: 1:39, non-stop
Boeing 737-800 (738)
American Airlines AA2121
05:00
Kansas City (MCI)

06:39
Chicago O'Hare (ORD) 3
Effective 2025-06-14 through 2025-07-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:39, non-stop
Boeing 737-800 (738)
American Airlines AA2121
05:44
Kansas City (MCI)

07:25
Chicago O'Hare (ORD) 3
Effective 2025-07-05 through 2025-08-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:41, non-stop
Boeing 737-800 (738)
American Airlines AA2121
06:00
Tampa (TPA)

07:10
Miami (MIA)
Effective 2025-10-26 through 2025-11-01
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:10, non-stop
Boeing 737 MAX 8 (7M8)
American Airlines AA2121
12:25
Chicago O'Hare (ORD) 3

15:44
Boston Logan (BOS) B
Effective 2026-01-07 through 2026-02-11
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:19, non-stop
Boeing 737-800 (738)
American Airlines AA2121
15:00
Ronald Reagan Washington (DCA) 2

16:17
Pittsburgh (PIT)
Valid until 2025-05-04
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Duration: 1:17, non-stop
Airbus A319 (319)
American Airlines AA2121
15:15
Phoenix Sky Harbor (PHX) 4

22:01
Detroit (DTW) E
Effective 2025-08-06 through 2025-09-02
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 3:46, non-stop
Boeing 737-800 (738)
American Airlines AA2121
15:15
Phoenix Sky Harbor (PHX) 4

22:04
Detroit (DTW) E
Effective 2025-09-03 through 2025-10-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 3:49, non-stop
Boeing 737-800 (738)
American Airlines AA2121
16:09
Phoenix Sky Harbor (PHX) 4

22:59
Detroit (DTW) E
Effective 2025-05-05 through 2025-05-24
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 3:50, non-stop
Boeing 737-800 (738)
American Airlines AA2121
16:09
Phoenix Sky Harbor (PHX) 4

22:59
Detroit (DTW) E
Effective 2025-05-26 through 2025-06-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 3:50, non-stop
Boeing 737-800 (738)
American Airlines AA2121
16:35
Phoenix Sky Harbor (PHX) 4

23:22
Detroit (DTW) E
Effective 2025-10-06 through 2025-10-25
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 3:47, non-stop
Boeing 737-800 (738)
American Airlines AA2121
17:02
Pittsburgh (PIT)

18:14
Ronald Reagan Washington (DCA) 2
Valid until 2025-05-04
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Duration: 1:12, non-stop
Airbus A319 (319)
American Airlines AA2121
21:20
Phoenix Sky Harbor (PHX) 4

22:04
Fresno (FAT)
Effective 2025-11-02 through 2025-12-17
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:44, non-stop
Airbus A320 (320)
American Airlines AA2121
21:20
Phoenix Sky Harbor (PHX) 4

22:09
Fresno (FAT)
Effective 2025-12-18 through 2026-01-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:49, non-stop
Airbus A320 (320)
American Airlines AA2121
21:20
Phoenix Sky Harbor (PHX) 4

22:03
Fresno (FAT)
Effective from 2026-02-12
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:43, non-stop
Airbus A320 (320)
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This flight number is listed as serving the following routes:
  • Chicago O'Hare (ORD) - Boston Logan (BOS)
  • Kansas City (MCI) - Chicago O'Hare (ORD)
  • Phoenix Sky Harbor (PHX) - Detroit (DTW)
  • Phoenix Sky Harbor (PHX) - Fresno (FAT)
  • Ronald Reagan Washington (DCA) - Pittsburgh (PIT)
  • Tampa (TPA) - Miami (MIA)
All American Airlines flights
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