American Airlines flight AA 4280: Multiple routes

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Select flight date:
FLIGHT SCHEDULE
Direct Flights:
Daily 07:00 Chicago O'Hare (ORD) 3 08:43 Kansas City (MCI)
AA 4280 Non-stop Embraer EMB 175 (E75) 1:43 Effective 2025-10-06 through 2025-11-01
Mon,Wed-Fri,Sun 07:05 Chicago O'Hare (ORD) 3 08:51 Kansas City (MCI)
AA 4280 Non-stop Embraer EMB 175 (E75) 1:46 Valid until 2025-05-04
Daily 08:00 Chicago O'Hare (ORD) 3 09:45 Kansas City (MCI)
AA 4280 Non-stop Embraer EMB 170 / EMB 175 (E70) 1:45 Effective 2025-12-03 through 2025-12-17
Daily 08:00 Chicago O'Hare (ORD) 3 09:47 Kansas City (MCI)
AA 4280 Non-stop Embraer EMB 170 / EMB 175 (E70) 1:47 Effective 2026-01-06 through 2026-02-11
Tue,Sat 08:20 Chicago O'Hare (ORD) 3 10:03 Kansas City (MCI)
AA 4280 Non-stop Embraer EMB 170 / EMB 175 (E70) 1:43 Valid until 2025-05-03
Mon,Wed-Fri,Sun 09:25 Kansas City (MCI) 11:00 Chicago O'Hare (ORD) 3
AA 4280 Non-stop Embraer EMB 175 (E75) 1:35 Valid until 2025-05-04
Daily 10:21 Chicago O'Hare (ORD) 3 11:57 Kansas City (MCI)
AA 4280 Non-stop Embraer EMB 175 (E75) 1:36 Effective 2025-07-05 through 2025-08-05
Daily 10:21 Chicago O'Hare (ORD) 3 11:57 Kansas City (MCI)
AA 4280 Non-stop Embraer EMB 175 (E75) 1:36 Effective 2025-09-03 through 2025-10-05
Mon-Fri,Sun 10:53 Chicago O'Hare (ORD) 3 12:44 Kansas City (MCI)
AA 4280 Non-stop Embraer EMB 175 (E75) 1:51 Effective 2025-06-05 through 2025-07-04
Sat 10:57 Chicago O'Hare (ORD) 3 12:48 Kansas City (MCI)
AA 4280 Non-stop Embraer EMB 175 (E75) 1:51 Effective 2025-06-07 through 2025-06-28
Daily 11:04 Kansas City (MCI) 12:40 Chicago O'Hare (ORD) 3
AA 4280 Non-stop Embraer EMB 175 (E75) 1:36 Effective 2025-10-06 through 2025-11-01
Tue,Sat 12:20 Kansas City (MCI) 13:55 Chicago O'Hare (ORD) 3
AA 4280 Non-stop Embraer EMB 170 / EMB 175 (E70) 1:35 Valid until 2025-05-03
Daily 12:39 Kansas City (MCI) 14:20 Chicago O'Hare (ORD) 3
AA 4280 Non-stop Embraer EMB 175 (E75) 1:41 Effective 2025-07-05 through 2025-08-05
Daily 12:39 Kansas City (MCI) 14:20 Chicago O'Hare (ORD) 3
AA 4280 Non-stop Embraer EMB 175 (E75) 1:41 Effective 2025-09-03 through 2025-10-05
Mon-Fri,Sun 13:14 Kansas City (MCI) 14:53 Chicago O'Hare (ORD) 3
AA 4280 Non-stop Embraer EMB 175 (E75) 1:39 Effective 2025-06-05 through 2025-07-04
Sat 13:19 Kansas City (MCI) 14:58 Chicago O'Hare (ORD) 3
AA 4280 Non-stop Embraer EMB 175 (E75) 1:39 Effective 2025-06-07 through 2025-06-28
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This flight number is listed as serving the following routes:


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American Airlines flight AA 4280: Multiple routes
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Select flight date:
FLIGHT SCHEDULE
Direct Flights:
American Airlines AA4280
07:00
Chicago O'Hare (ORD) 3

08:43
Kansas City (MCI)
Effective 2025-10-06 through 2025-11-01
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:43, non-stop
Embraer EMB 175 (E75)
American Airlines AA4280
07:05
Chicago O'Hare (ORD) 3

08:51
Kansas City (MCI)
Valid until 2025-05-04
Mon
Tue
-
Wed
Thu
Fri
Sat
-
Sun
Duration: 1:46, non-stop
Embraer EMB 175 (E75)
American Airlines AA4280
08:00
Chicago O'Hare (ORD) 3

09:45
Kansas City (MCI)
Effective 2025-12-03 through 2025-12-17
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:45, non-stop
Embraer EMB 170 / EMB 175 (E70)
American Airlines AA4280
08:00
Chicago O'Hare (ORD) 3

09:47
Kansas City (MCI)
Effective 2026-01-06 through 2026-02-11
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:47, non-stop
Embraer EMB 170 / EMB 175 (E70)
American Airlines AA4280
08:20
Chicago O'Hare (ORD) 3

10:03
Kansas City (MCI)
Valid until 2025-05-03
Mon
-
Tue
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Duration: 1:43, non-stop
Embraer EMB 170 / EMB 175 (E70)
American Airlines AA4280
09:25
Kansas City (MCI)

11:00
Chicago O'Hare (ORD) 3
Valid until 2025-05-04
Mon
Tue
-
Wed
Thu
Fri
Sat
-
Sun
Duration: 1:35, non-stop
Embraer EMB 175 (E75)
American Airlines AA4280
10:21
Chicago O'Hare (ORD) 3

11:57
Kansas City (MCI)
Effective 2025-07-05 through 2025-08-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:36, non-stop
Embraer EMB 175 (E75)
American Airlines AA4280
10:21
Chicago O'Hare (ORD) 3

11:57
Kansas City (MCI)
Effective 2025-09-03 through 2025-10-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:36, non-stop
Embraer EMB 175 (E75)
American Airlines AA4280
10:53
Chicago O'Hare (ORD) 3

12:44
Kansas City (MCI)
Effective 2025-06-05 through 2025-07-04
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Duration: 1:51, non-stop
Embraer EMB 175 (E75)
American Airlines AA4280
10:57
Chicago O'Hare (ORD) 3

12:48
Kansas City (MCI)
Effective 2025-06-07 through 2025-06-28
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Duration: 1:51, non-stop
Embraer EMB 175 (E75)
American Airlines AA4280
11:04
Kansas City (MCI)

12:40
Chicago O'Hare (ORD) 3
Effective 2025-10-06 through 2025-11-01
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:36, non-stop
Embraer EMB 175 (E75)
American Airlines AA4280
12:20
Kansas City (MCI)

13:55
Chicago O'Hare (ORD) 3
Valid until 2025-05-03
Mon
-
Tue
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Duration: 1:35, non-stop
Embraer EMB 170 / EMB 175 (E70)
American Airlines AA4280
12:39
Kansas City (MCI)

14:20
Chicago O'Hare (ORD) 3
Effective 2025-07-05 through 2025-08-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:41, non-stop
Embraer EMB 175 (E75)
American Airlines AA4280
12:39
Kansas City (MCI)

14:20
Chicago O'Hare (ORD) 3
Effective 2025-09-03 through 2025-10-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:41, non-stop
Embraer EMB 175 (E75)
American Airlines AA4280
13:14
Kansas City (MCI)

14:53
Chicago O'Hare (ORD) 3
Effective 2025-06-05 through 2025-07-04
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Duration: 1:39, non-stop
Embraer EMB 175 (E75)
American Airlines AA4280
13:19
Kansas City (MCI)

14:58
Chicago O'Hare (ORD) 3
Effective 2025-06-07 through 2025-06-28
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Duration: 1:39, non-stop
Embraer EMB 175 (E75)
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This flight number is listed as serving the following routes:
  • Kansas City (MCI) - Chicago O'Hare (ORD)
All American Airlines flights
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