American Airlines flight AA 4427: Multiple routes

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FLIGHT SCHEDULE
Direct Flights:
Daily 05:45 New Orleans (MSY) 08:22 Chicago O'Hare (ORD) 3
AA 4427 Non-stop Embraer EMB 175 (E75) 2:37 Effective 2025-09-03 through 2025-10-05
Fri 16:00 New York LaGuardia (LGA) B 17:57 Raleigh/Durham (RDU) 2
AA 4427 Non-stop Embraer EMB 175 (E75) 1:57 Effective 2025-07-11 through 2025-08-01
Sat 16:07 New York LaGuardia (LGA) B 18:01 Raleigh/Durham (RDU) 2
AA 4427 Non-stop Embraer EMB 175 (E75) 1:54 Effective 2025-06-07 through 2025-06-28
Mon-Fri,Sun 16:09 New York LaGuardia (LGA) B 18:00 Raleigh/Durham (RDU) 2
AA 4427 Non-stop Embraer EMB 175 (E75) 1:51 Effective 2025-06-05 through 2025-07-04
Sat 16:09 New York LaGuardia (LGA) B 18:07 Raleigh/Durham (RDU) 2
AA 4427 Non-stop Embraer EMB 175 (E75) 1:58 Effective 2025-07-05 through 2025-08-02
Mon-Thu,Sun 16:09 New York LaGuardia (LGA) B 18:06 Raleigh/Durham (RDU) 2
AA 4427 Non-stop Embraer EMB 175 (E75) 1:57 Effective 2025-07-06 through 2025-08-05
Daily 18:15 New York LaGuardia (LGA) B 20:30 Indianapolis (IND)
AA 4427 Non-stop Embraer EMB 175 (E75) 2:15 Effective 2025-10-26 through 2025-11-01
Daily 18:30 New York LaGuardia (LGA) B 20:45 Indianapolis (IND)
AA 4427 Non-stop Embraer EMB 175 (E75) 2:15 Effective 2025-08-06 through 2025-09-02
Daily 18:30 New York LaGuardia (LGA) B 20:48 Indianapolis (IND)
AA 4427 Non-stop Embraer EMB 170 / EMB 175 (E70) 2:18 Effective 2025-12-18 through 2026-01-05
Mon-Fri,Sun 19:40 New York LaGuardia (LGA) B 22:00 Indianapolis (IND)
AA 4427 Non-stop Embraer EMB 170 / EMB 175 (E70) 2:20 Valid until 2025-05-04
Daily 19:40 New York LaGuardia (LGA) B 22:01 Indianapolis (IND)
AA 4427 Non-stop Embraer EMB 170 / EMB 175 (E70) 2:21 Effective 2025-12-03 through 2025-12-17
Daily 19:45 New York LaGuardia (LGA) B 22:12 Indianapolis (IND)
AA 4427 Non-stop Embraer EMB 170 / EMB 175 (E70) 2:27 Effective 2025-11-02 through 2025-12-02
Daily 19:55 New York LaGuardia (LGA) B 22:26 Indianapolis (IND)
AA 4427 Non-stop Embraer EMB 170 / EMB 175 (E70) 2:31 Effective from 2026-02-12
Mon-Fri,Sun 19:59 New York LaGuardia (LGA) B 22:11 Indianapolis (IND)
AA 4427 Non-stop Embraer EMB 170 / EMB 175 (E70) 2:12 Effective 2025-05-05 through 2025-06-04
Daily 19:59 New York LaGuardia (LGA) B 22:27 Indianapolis (IND)
AA 4427 Non-stop Embraer EMB 170 / EMB 175 (E70) 2:28 Effective 2026-01-06 through 2026-02-11
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This flight number is listed as serving the following routes:


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American Airlines flight AA 4427: Multiple routes
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Select flight date:
FLIGHT SCHEDULE
Direct Flights:
American Airlines AA4427
05:45
New Orleans (MSY)

08:22
Chicago O'Hare (ORD) 3
Effective 2025-09-03 through 2025-10-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:37, non-stop
Embraer EMB 175 (E75)
American Airlines AA4427
16:00
New York LaGuardia (LGA) B

17:57
Raleigh/Durham (RDU) 2
Effective 2025-07-11 through 2025-08-01
Mon
-
Tue
-
Wed
-
Thu
-
Fri
Sat
-
Sun
-
Duration: 1:57, non-stop
Embraer EMB 175 (E75)
American Airlines AA4427
16:07
New York LaGuardia (LGA) B

18:01
Raleigh/Durham (RDU) 2
Effective 2025-06-07 through 2025-06-28
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Duration: 1:54, non-stop
Embraer EMB 175 (E75)
American Airlines AA4427
16:09
New York LaGuardia (LGA) B

18:00
Raleigh/Durham (RDU) 2
Effective 2025-06-05 through 2025-07-04
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Duration: 1:51, non-stop
Embraer EMB 175 (E75)
American Airlines AA4427
16:09
New York LaGuardia (LGA) B

18:07
Raleigh/Durham (RDU) 2
Effective 2025-07-05 through 2025-08-02
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Duration: 1:58, non-stop
Embraer EMB 175 (E75)
American Airlines AA4427
16:09
New York LaGuardia (LGA) B

18:06
Raleigh/Durham (RDU) 2
Effective 2025-07-06 through 2025-08-05
Mon
Tue
Wed
Thu
Fri
-
Sat
-
Sun
Duration: 1:57, non-stop
Embraer EMB 175 (E75)
American Airlines AA4427
18:15
New York LaGuardia (LGA) B

20:30
Indianapolis (IND)
Effective 2025-10-26 through 2025-11-01
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:15, non-stop
Embraer EMB 175 (E75)
American Airlines AA4427
18:30
New York LaGuardia (LGA) B

20:45
Indianapolis (IND)
Effective 2025-08-06 through 2025-09-02
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:15, non-stop
Embraer EMB 175 (E75)
American Airlines AA4427
18:30
New York LaGuardia (LGA) B

20:48
Indianapolis (IND)
Effective 2025-12-18 through 2026-01-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:18, non-stop
Embraer EMB 170 / EMB 175 (E70)
American Airlines AA4427
19:40
New York LaGuardia (LGA) B

22:00
Indianapolis (IND)
Valid until 2025-05-04
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Duration: 2:20, non-stop
Embraer EMB 170 / EMB 175 (E70)
American Airlines AA4427
19:40
New York LaGuardia (LGA) B

22:01
Indianapolis (IND)
Effective 2025-12-03 through 2025-12-17
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:21, non-stop
Embraer EMB 170 / EMB 175 (E70)
American Airlines AA4427
19:45
New York LaGuardia (LGA) B

22:12
Indianapolis (IND)
Effective 2025-11-02 through 2025-12-02
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:27, non-stop
Embraer EMB 170 / EMB 175 (E70)
American Airlines AA4427
19:55
New York LaGuardia (LGA) B

22:26
Indianapolis (IND)
Effective from 2026-02-12
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:31, non-stop
Embraer EMB 170 / EMB 175 (E70)
American Airlines AA4427
19:59
New York LaGuardia (LGA) B

22:11
Indianapolis (IND)
Effective 2025-05-05 through 2025-06-04
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Duration: 2:12, non-stop
Embraer EMB 170 / EMB 175 (E70)
American Airlines AA4427
19:59
New York LaGuardia (LGA) B

22:27
Indianapolis (IND)
Effective 2026-01-06 through 2026-02-11
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:28, non-stop
Embraer EMB 170 / EMB 175 (E70)
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This flight number is listed as serving the following routes:
  • New Orleans (MSY) - Chicago O'Hare (ORD)
  • New York LaGuardia (LGA) - Indianapolis (IND)
  • New York LaGuardia (LGA) - Raleigh/Durham (RDU)
All American Airlines flights
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