American Airlines flight AA 4545: Multiple routes

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Select flight date:
FLIGHT SCHEDULE
Direct Flights:
Daily 09:40 Chicago O'Hare (ORD) 3 11:21 Minneapolis/Saint Paul (MSP) 1
AA 4545 Non-stop Embraer EMB 175 (E75) 1:41 Effective 2025-12-18 through 2026-01-05
Daily 09:40 Chicago O'Hare (ORD) 3 11:15 Minneapolis/Saint Paul (MSP) 1
AA 4545 Non-stop Embraer EMB 175 (E75) 1:35 Effective from 2026-02-12
Daily 12:22 New York LaGuardia (LGA) B 13:59 Raleigh/Durham (RDU) 2
AA 4545 Non-stop Embraer EMB 175 (E75) 1:37 Effective 2025-08-06 through 2025-09-02
Mon-Fri 12:26 New York LaGuardia (LGA) B 14:07 Raleigh/Durham (RDU) 2
AA 4545 Non-stop Embraer EMB 175 (E75) 1:41 Effective 2025-07-07 through 2025-08-05
Mon-Fri,Sun 12:29 New York LaGuardia (LGA) B 14:07 Raleigh/Durham (RDU) 2
AA 4545 Non-stop Embraer EMB 175 (E75) 1:38 Effective 2025-06-05 through 2025-07-03
Sun 12:29 New York LaGuardia (LGA) B 14:10 Raleigh/Durham (RDU) 2
AA 4545 Non-stop Embraer EMB 175 (E75) 1:41 Effective 2025-07-06 through 2025-08-03
Daily 12:41 Minneapolis/Saint Paul (MSP) 1 14:20 Chicago O'Hare (ORD) 3
AA 4545 Non-stop Embraer EMB 175 (E75) 1:39 Effective 2025-12-18 through 2026-01-05
Daily 12:45 Minneapolis/Saint Paul (MSP) 1 14:20 Chicago O'Hare (ORD) 3
AA 4545 Non-stop Embraer EMB 175 (E75) 1:35 Effective from 2026-02-12
Mon-Fri 14:38 Raleigh/Durham (RDU) 2 16:19 New York LaGuardia (LGA) B
AA 4545 Non-stop Embraer EMB 175 (E75) 1:41 Effective 2025-07-07 through 2025-08-05
Mon-Fri,Sun 14:42 Raleigh/Durham (RDU) 2 16:19 New York LaGuardia (LGA) B
AA 4545 Non-stop Embraer EMB 175 (E75) 1:37 Effective 2025-06-05 through 2025-07-03
Daily 14:42 Raleigh/Durham (RDU) 2 16:19 New York LaGuardia (LGA) B
AA 4545 Non-stop Embraer EMB 175 (E75) 1:37 Effective 2025-08-06 through 2025-09-02
Sun 14:54 Raleigh/Durham (RDU) 2 16:35 New York LaGuardia (LGA) B
AA 4545 Non-stop Embraer EMB 175 (E75) 1:41 Effective 2025-07-06 through 2025-08-03
Mon-Fri,Sun 18:30 Charleston (CHS) 20:05 Ronald Reagan Washington (DCA) 2
AA 4545 Non-stop Embraer EMB 175 (E75) 1:35 Effective 2025-05-05 through 2025-06-04
Daily 18:40 Charleston (CHS) 20:17 Ronald Reagan Washington (DCA) 2
AA 4545 Non-stop Embraer EMB 175 (E75) 1:37 Valid until 2025-05-04
Sat 19:30 Charleston (CHS) 21:05 Ronald Reagan Washington (DCA) 2
AA 4545 Non-stop Embraer EMB 175 (E75) 1:35 Effective 2025-05-10 through 2025-05-31
Daily 21:00 Philadelphia (PHL) 22:44 John Glenn Columbus (CMH)
AA 4545 Non-stop Embraer EMB 175 (E75) 1:44 Effective 2025-10-26 through 2025-11-01
Daily 21:00 Philadelphia (PHL) 22:50 John Glenn Columbus (CMH)
AA 4545 Non-stop Embraer EMB 175 (E75) 1:50 Effective 2025-11-02 through 2025-12-02
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This flight number is listed as serving the following routes:


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American Airlines flight AA 4545: Multiple routes
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Select flight date:
FLIGHT SCHEDULE
Direct Flights:
American Airlines AA4545
09:40
Chicago O'Hare (ORD) 3

11:21
Minneapolis/Saint Paul (MSP) 1
Effective 2025-12-18 through 2026-01-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:41, non-stop
Embraer EMB 175 (E75)
American Airlines AA4545
09:40
Chicago O'Hare (ORD) 3

11:15
Minneapolis/Saint Paul (MSP) 1
Effective from 2026-02-12
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:35, non-stop
Embraer EMB 175 (E75)
American Airlines AA4545
12:22
New York LaGuardia (LGA) B

13:59
Raleigh/Durham (RDU) 2
Effective 2025-08-06 through 2025-09-02
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:37, non-stop
Embraer EMB 175 (E75)
American Airlines AA4545
12:26
New York LaGuardia (LGA) B

14:07
Raleigh/Durham (RDU) 2
Effective 2025-07-07 through 2025-08-05
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
-
Duration: 1:41, non-stop
Embraer EMB 175 (E75)
American Airlines AA4545
12:29
New York LaGuardia (LGA) B

14:07
Raleigh/Durham (RDU) 2
Effective 2025-06-05 through 2025-07-03
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Duration: 1:38, non-stop
Embraer EMB 175 (E75)
American Airlines AA4545
12:29
New York LaGuardia (LGA) B

14:10
Raleigh/Durham (RDU) 2
Effective 2025-07-06 through 2025-08-03
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
-
Sun
Duration: 1:41, non-stop
Embraer EMB 175 (E75)
American Airlines AA4545
12:41
Minneapolis/Saint Paul (MSP) 1

14:20
Chicago O'Hare (ORD) 3
Effective 2025-12-18 through 2026-01-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:39, non-stop
Embraer EMB 175 (E75)
American Airlines AA4545
12:45
Minneapolis/Saint Paul (MSP) 1

14:20
Chicago O'Hare (ORD) 3
Effective from 2026-02-12
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:35, non-stop
Embraer EMB 175 (E75)
American Airlines AA4545
14:38
Raleigh/Durham (RDU) 2

16:19
New York LaGuardia (LGA) B
Effective 2025-07-07 through 2025-08-05
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
-
Duration: 1:41, non-stop
Embraer EMB 175 (E75)
American Airlines AA4545
14:42
Raleigh/Durham (RDU) 2

16:19
New York LaGuardia (LGA) B
Effective 2025-06-05 through 2025-07-03
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Duration: 1:37, non-stop
Embraer EMB 175 (E75)
American Airlines AA4545
14:42
Raleigh/Durham (RDU) 2

16:19
New York LaGuardia (LGA) B
Effective 2025-08-06 through 2025-09-02
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:37, non-stop
Embraer EMB 175 (E75)
American Airlines AA4545
14:54
Raleigh/Durham (RDU) 2

16:35
New York LaGuardia (LGA) B
Effective 2025-07-06 through 2025-08-03
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
-
Sun
Duration: 1:41, non-stop
Embraer EMB 175 (E75)
American Airlines AA4545
18:30
Charleston (CHS)

20:05
Ronald Reagan Washington (DCA) 2
Effective 2025-05-05 through 2025-06-04
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Duration: 1:35, non-stop
Embraer EMB 175 (E75)
American Airlines AA4545
18:40
Charleston (CHS)

20:17
Ronald Reagan Washington (DCA) 2
Valid until 2025-05-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:37, non-stop
Embraer EMB 175 (E75)
American Airlines AA4545
19:30
Charleston (CHS)

21:05
Ronald Reagan Washington (DCA) 2
Effective 2025-05-10 through 2025-05-31
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Duration: 1:35, non-stop
Embraer EMB 175 (E75)
American Airlines AA4545
21:00
Philadelphia (PHL)

22:44
John Glenn Columbus (CMH)
Effective 2025-10-26 through 2025-11-01
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:44, non-stop
Embraer EMB 175 (E75)
American Airlines AA4545
21:00
Philadelphia (PHL)

22:50
John Glenn Columbus (CMH)
Effective 2025-11-02 through 2025-12-02
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:50, non-stop
Embraer EMB 175 (E75)
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This flight number is listed as serving the following routes:
  • Charleston (CHS) - Ronald Reagan Washington (DCA)
  • Chicago O'Hare (ORD) - Minneapolis/Saint Paul (MSP)
  • New York LaGuardia (LGA) - Raleigh/Durham (RDU)
  • Philadelphia (PHL) - John Glenn Columbus (CMH)
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