KLM flight KL 6421: Multiple routes

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Select flight date:
FLIGHT SCHEDULE
Direct Codeshare Flights:
Daily 06:00 Sacramento (SMF) A 07:43 Los Angeles (LAX) 3
KL 6421 Non-stop Embraer EMB 175 (E7W) 1:43 Effective 2025-11-02 through 2025-12-19
Codeshare flight, operated by Delta Air Lines.(DL 3782)
Daily 09:10 Sacramento (SMF) A 10:49 Los Angeles (LAX) 3
KL 6421 Non-stop Embraer EMB 175 (E7W) 1:39 Effective from 2026-01-06
Codeshare flight, operated by Delta Air Lines.(DL 3822)
Daily 10:35 Sacramento (SMF) A 12:13 Los Angeles (LAX) 3
KL 6421 Non-stop Embraer EMB 175 (E7W) 1:38 Effective 2025-12-20 through 2026-01-05
Codeshare flight, operated by Delta Air Lines.(DL 3755)
Daily 11:10 Sacramento (SMF) A 12:51 Los Angeles (LAX) 3
KL 6421 Non-stop Embraer EMB 175 (E7W) 1:41 Effective 2025-10-26 through 2025-11-01
Codeshare flight, operated by Delta Air Lines.(DL 3755)
Mon-Thu,Sun 15:50 Detroit (DTW) M 16:32 Saint Louis (STL) 1
KL 6421 Non-stop Canadair CRJ 900 (CR9) 1:42 Effective 2025-06-29 through 2025-07-03
Codeshare flight, operated by Delta Air Lines.(DL 3934)
Sat 15:55 Detroit (DTW) M 16:37 Saint Louis (STL) 1
KL 6421 Non-stop Canadair CRJ 900 (CR9) 1:42 Effective 2025-05-10 through 2025-05-17
Codeshare flight, operated by Delta Air Lines.(DL 3709)
Sat 15:55 Detroit (DTW) M 16:37 Saint Louis (STL) 1
KL 6421 Non-stop Canadair CRJ 900 (CR9) 1:42 Effective 2025-05-31 through 2025-06-07
Codeshare flight, operated by Delta Air Lines.(DL 3709)
Sat 17:45 Detroit (DTW) M 18:20 Saint Louis (STL) 1
KL 6421 Non-stop Boeing 717 (717) 1:35 Effective 2025-07-12 through 2025-08-09
Codeshare flight, operated by Delta Air Lines.(DL 1541)
Mon-Thu,Sun 17:54 Saint Louis (STL) 1 20:33 Detroit (DTW) M
KL 6421 Non-stop Canadair CRJ 900 (CR9) 1:39 Effective 2025-06-29 through 2025-07-03
Codeshare flight, operated by Delta Air Lines.(DL 3934)
Sat 19:50 Detroit (DTW) M 20:30 Saint Louis (STL) 1
KL 6421 Non-stop Boeing 717 (717) 1:40 Effective 2025-06-14 through 2025-06-28
Codeshare flight, operated by Delta Air Lines.(DL 1541)
Fri,Sat 19:50 Detroit (DTW) M 20:30 Saint Louis (STL) 1
KL 6421 Non-stop Boeing 717 (717) 1:40 Effective 2025-07-04 through 2025-07-05
Codeshare flight, operated by Delta Air Lines.(DL 1541)
Mon-Fri,Sun 19:55 Detroit (DTW) M 20:30 Saint Louis (STL) 1
KL 6421 Non-stop Boeing 717 (717) 1:35 Effective 2025-07-07 through 2025-08-29
Codeshare flight, operated by Delta Air Lines.(DL 1541)
Mon-Fri,Sun 19:55 Detroit (DTW) M 20:30 Saint Louis (STL) 1
KL 6421 Non-stop Boeing 717 (717) 1:35 Effective 2025-09-01 through 2025-09-07
Codeshare flight, operated by Delta Air Lines.(DL 1541)
Daily 19:55 Detroit (DTW) M 20:35 Saint Louis (STL) 1
KL 6421 Non-stop Boeing 717 (717) 1:40 Effective 2025-09-08 through 2025-10-25
Codeshare flight, operated by Delta Air Lines.(DL 1541)
Mon-Fri,Sun 20:00 Detroit (DTW) M 20:40 Saint Louis (STL) 1
KL 6421 Non-stop Boeing 717 (717) 1:40 Effective 2025-06-08 through 2025-06-27
Codeshare flight, operated by Delta Air Lines.(DL 1541)
Sun 20:00 Detroit (DTW) M 20:40 Saint Louis (STL) 1
KL 6421 Non-stop Boeing 717 (717) 1:40 Operates only on 2025-07-06
Codeshare flight, operated by Delta Air Lines.(DL 1541)
Mon-Fri,Sun 20:11 Detroit (DTW) M 20:49 Saint Louis (STL) 1
KL 6421 Non-stop Boeing 717 (717) 1:38 Effective 2025-05-07 through 2025-05-23
Codeshare flight, operated by Delta Air Lines.(DL 1541)
Mon-Fri,Sun 20:11 Detroit (DTW) M 20:49 Saint Louis (STL) 1
KL 6421 Non-stop Boeing 717 (717) 1:38 Effective 2025-05-26 through 2025-06-06
Codeshare flight, operated by Delta Air Lines.(DL 1541)
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This flight number is listed as serving the following routes:


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KLM flight KL 6421: Multiple routes
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Select flight date:
FLIGHT SCHEDULE
Direct Codeshare Flights:
KLM KL6421
06:00
Sacramento (SMF) A

07:43
Los Angeles (LAX) 3
Effective 2025-11-02 through 2025-12-19
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by Delta Air Lines. (DL 3782)
Duration: 1:43, non-stop
Embraer EMB 175 (E7W)
KLM KL6421
09:10
Sacramento (SMF) A

10:49
Los Angeles (LAX) 3
Effective from 2026-01-06
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by Delta Air Lines. (DL 3822)
Duration: 1:39, non-stop
Embraer EMB 175 (E7W)
KLM KL6421
10:35
Sacramento (SMF) A

12:13
Los Angeles (LAX) 3
Effective 2025-12-20 through 2026-01-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by Delta Air Lines. (DL 3755)
Duration: 1:38, non-stop
Embraer EMB 175 (E7W)
KLM KL6421
11:10
Sacramento (SMF) A

12:51
Los Angeles (LAX) 3
Effective 2025-10-26 through 2025-11-01
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by Delta Air Lines. (DL 3755)
Duration: 1:41, non-stop
Embraer EMB 175 (E7W)
KLM KL6421
15:50
Detroit (DTW) M

16:32
Saint Louis (STL) 1
Effective 2025-06-29 through 2025-07-03
Mon
Tue
Wed
Thu
Fri
-
Sat
-
Sun
Codeshare flight, operated by Delta Air Lines. (DL 3934)
Duration: 1:42, non-stop
Canadair CRJ 900 (CR9)
KLM KL6421
15:55
Detroit (DTW) M

16:37
Saint Louis (STL) 1
Effective 2025-05-10 through 2025-05-17
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Codeshare flight, operated by Delta Air Lines. (DL 3709)
Duration: 1:42, non-stop
Canadair CRJ 900 (CR9)
KLM KL6421
15:55
Detroit (DTW) M

16:37
Saint Louis (STL) 1
Effective 2025-05-31 through 2025-06-07
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Codeshare flight, operated by Delta Air Lines. (DL 3709)
Duration: 1:42, non-stop
Canadair CRJ 900 (CR9)
KLM KL6421
17:45
Detroit (DTW) M

18:20
Saint Louis (STL) 1
Effective 2025-07-12 through 2025-08-09
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Codeshare flight, operated by Delta Air Lines. (DL 1541)
Duration: 1:35, non-stop
Boeing 717 (717)
KLM KL6421
17:54
Saint Louis (STL) 1

20:33
Detroit (DTW) M
Effective 2025-06-29 through 2025-07-03
Mon
Tue
Wed
Thu
Fri
-
Sat
-
Sun
Codeshare flight, operated by Delta Air Lines. (DL 3934)
Duration: 1:39, non-stop
Canadair CRJ 900 (CR9)
KLM KL6421
19:50
Detroit (DTW) M

20:30
Saint Louis (STL) 1
Effective 2025-06-14 through 2025-06-28
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Codeshare flight, operated by Delta Air Lines. (DL 1541)
Duration: 1:40, non-stop
Boeing 717 (717)
KLM KL6421
19:50
Detroit (DTW) M

20:30
Saint Louis (STL) 1
Effective 2025-07-04 through 2025-07-05
Mon
-
Tue
-
Wed
-
Thu
-
Fri
Sat
Sun
-
Codeshare flight, operated by Delta Air Lines. (DL 1541)
Duration: 1:40, non-stop
Boeing 717 (717)
KLM KL6421
19:55
Detroit (DTW) M

20:30
Saint Louis (STL) 1
Effective 2025-07-07 through 2025-08-29
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Codeshare flight, operated by Delta Air Lines. (DL 1541)
Duration: 1:35, non-stop
Boeing 717 (717)
KLM KL6421
19:55
Detroit (DTW) M

20:30
Saint Louis (STL) 1
Effective 2025-09-01 through 2025-09-07
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Codeshare flight, operated by Delta Air Lines. (DL 1541)
Duration: 1:35, non-stop
Boeing 717 (717)
KLM KL6421
19:55
Detroit (DTW) M

20:35
Saint Louis (STL) 1
Effective 2025-09-08 through 2025-10-25
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by Delta Air Lines. (DL 1541)
Duration: 1:40, non-stop
Boeing 717 (717)
KLM KL6421
20:00
Detroit (DTW) M

20:40
Saint Louis (STL) 1
Effective 2025-06-08 through 2025-06-27
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Codeshare flight, operated by Delta Air Lines. (DL 1541)
Duration: 1:40, non-stop
Boeing 717 (717)
KLM KL6421
20:00
Detroit (DTW) M

20:40
Saint Louis (STL) 1
Operates only on 2025-07-06
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
-
Sun
Codeshare flight, operated by Delta Air Lines. (DL 1541)
Duration: 1:40, non-stop
Boeing 717 (717)
KLM KL6421
20:11
Detroit (DTW) M

20:49
Saint Louis (STL) 1
Effective 2025-05-07 through 2025-05-23
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Codeshare flight, operated by Delta Air Lines. (DL 1541)
Duration: 1:38, non-stop
Boeing 717 (717)
KLM KL6421
20:11
Detroit (DTW) M

20:49
Saint Louis (STL) 1
Effective 2025-05-26 through 2025-06-06
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Codeshare flight, operated by Delta Air Lines. (DL 1541)
Duration: 1:38, non-stop
Boeing 717 (717)
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This flight number is listed as serving the following routes:
  • Sacramento (SMF) - Los Angeles (LAX)
  • Saint Louis (STL) - Detroit (DTW)
All KLM flights
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